The Hermle-Benchmark Z446 Series is built for labs that handle serious volume. With room for 4 × 750 mL swing-out rotors, it takes on everything from 15 mL conical tubes to large tissue culture bottles and even microplates — all in one compact, benchtop footprint. Designed with advanced rotor recognition and optional refrigeration, it’s a versatile centrifuge that gives researchers precision and power without compromise.
The Hermle-Benchmark Z446 Series High Capacity Centrifuge brings high-volume performance, intuitive control, and unmatched flexibility to the benchtop. From everyday separations to specialized culture work, it delivers consistent results with effortless precision.
When space is limited but workloads aren’t, the Z446 keeps productivity high. Its maximum capacity of 4 × 750 mL makes it the largest in the Hermle–Benchmark benchtop lineup, delivering dependable results for high-throughput applications like cell culture, bioprocessing, and sample preparation. The rotor’s aircraft-grade alloy construction handles up to 4,500 × g with confidence, and advanced airflow ensures stable, uniform runs even under heavy loads.
Available in both standard and refrigerated (-K) versions, the Z446 adapts easily to temperature-sensitive workflows. The Z446-K model provides a cooling range from -20°C to +40°C, ensuring sample integrity from start to finish.
Precision is built into every run. The Z446’s microprocessor-based interface automatically recognizes installed rotors, preventing overspeeding and instantly displaying the correct RCF. With simple touch controls, users can fine-tune acceleration and deceleration profiles, adjust alarm tones, and store frequently used programs for quick recall.
Rotor changes are fast — less than a minute with the included wrench — and the bright backlit LCD display confirms every setting at a glance. It’s the kind of thoughtful design that reduces downtime and keeps workflows moving smoothly.
From cell culture to microplate work, the Z446 offers a complete rotor lineup to meet diverse lab needs:
4 × 750 mL swing-out rotor for large-volume processing
Sealable microplate carriers and PCR adapters for assay and molecular workflows
Conical, round, and microtube rotors ranging from 1.5 mL to 500 mL
Universal adapters for chamber slides and dishes
With options for up to 68 × 15 mL or 28 × 50 mL tubes, the Z446 adapts easily to changing protocols and growing demand.
Every detail of the Z446 is engineered for reliability. Its reinforced chassis minimizes vibration, the rotor chamber resists wear, and cooling efficiency remains steady through long runs. Whether standard or refrigerated, it’s a centrifuge designed to keep up with the pace of modern labs — durable, quiet, and easy to maintain.
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